52-794-81MG

MilliporeSigma™ Calbiochem™ Piceatannol

Manufacturer: MilliporeSigma™

CAS Number: 10083-24-6

Select a Size

Pack Size SKU Availability Price
Each of 1 52-794-81MG-Each-of-1 In Stock ₹ 6,684.80

52-794-81MG - Each of 1

₹ 6,684.80

In Stock

Quantity

1

Base Price: ₹ 6,684.80

GST (18%): ₹ 1,203.264

Total Price: ₹ 7,888.064

Color

Off-white

Target Proteins

Activity of rat liver protein kinase A catalytic subunit

Molecular Formula

C14H12O4

Solubility

DMSO or EtOH

Form

Crystalline Solid

Description

95% by HPLC

CAS

10083-24-6

Formula Weight

244.2g/mol

Content And Storage

Protect from light

Quantity

1 mg

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Description

  • A cell-permeable, substrate competitive and reversible plant metabolite that inhibits the activity of rat liver protein kinase A catalytic subunit (IC 50 = 3μM), PKC (IC 50 = 8μM), MLCK (IC 50 = 12μM)
  • In RBL-2H3 cells, the selective inhibition of Syk by piceatannol results in inhibition of FceR1-mediated signaling
  • Also inhibits wheat embryo Ca 2+ -dependent protein kinase (CDPK) (IC 50 = 19μM), and p72 syk (IC 50 = 10μM), a non-receptor tyrosine kinase, relative to Lyn in isolated enzyme preparations
  • Also possesses anti-leukemic properties
  • Reported to activate sirtuins and promote the survival of eukaryotic cells.