57-312-110MG
MilliporeSigma™ Calbiochem™ SMER28
Manufacturer: MilliporeSigma™
CAS Number: 307538-42-7
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 57-312-110MG-Each-of-1 | In Stock | ₹ 17,335.31 |
57-312-110MG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,335.31
GST (18%): ₹ 3,120.356
Total Price: ₹ 20,455.666
Color
Pale Yellow
CAS
307538-42-7
Formula Weight
264.1g/mol
Content And Storage
Protect from light
Quantity
10 mg
Description
95% by HPLC
Molecular Formula
C11H10BrN3
Solubility
DMSO or EtOH
Form
Solid
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | eMolecules Medchem Express / SMER28 / 5mg / 446255082 / HY-100200 / / 307538-42-7 / MFCD02166825 / 264.126 / C11H10BrN3 | -- | ₹ 7,178.48 | |
| | Sigma Aldrich Fine Chemicals Biosciences SMER28 >99% (HPLC), solid | Purity: >99% (HPLC) | Mol Wt: 264.12 | 307538-42-7 | MFCD02166825 | 5MG | -- | ₹ 18,761.60 | |
| | Sigma Aldrich Fine Chemicals Biosciences SMER28 >99% (HPLC), solid | Purity: >99% (HPLC) | Mol Wt: 264.12 | 307538-42-7 | MFCD02166825 | 25MG | -- | ₹ 81,273.44 | |
| | 4-Quinazolinamine, 6-bromo-N-2-propen-1-yl- | -- | ₹ 4,363.56 - ₹ 22,245.60 | |
| | 307538-42-7 | Smer28 | -- | ₹ 3,850.20 - ₹ 54,758.40 |
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Description
- A cell-permeable quinazoline compound that augments the cytostatic effects of Rapamycin (Cat
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- 553210 and 553211) in Saccharomyces cerevisiae and acts as an autophagy stimulator both in mammalian cultures in vitro and in a Drosophila melanogaster HD model in vivo
- Although SMER28 and Rapamycin do exhibit additive effects on the clearance of cellular autophagy substrates, SMER28 functions independently of Rapamycin by presumably acting on celluar target(s) downstream of the Rapamycin/FKBP12 target, mTOR.