61-430-510MG
MilliporeSigma™ Calbiochem™ TLR1/TLR2 Antagonist, CU-CPT22
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 61-430-510MG-Each-of-1 | In Stock | ₹ 18,340.64 |
61-430-510MG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 18,340.64
GST (18%): ₹ 3,301.315
Total Price: ₹ 21,641.955
Color
Orange
Target Proteins
TLR1
Formula Weight
362.4g/mol
Content And Storage
Protect from light
Quantity
10 mg
Description
98% by HPLC
Molecular Formula
C19H22O7
Solubility
DMSO
Form
Solid
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Description
- A cell-permeable benzotropolone compound that competes against Pam 3 CSK 4 - (Cat
- No
- 506350) for TLR1/TLR2 heterodimer binding ( K i = 410nM) and selectively antagonizes against Pam 3 CSK 4 -induced RAW264.7 cellular NO production (IC 50 = 580nM) without apparent cytotoxicity ( up to 100μM and 24 h)
- Exhibits no antagonist activity toward TLR2/TLR6, TLR3, TLR4, TLR7 at 0.5μM and little inhibitory potency against a panel of 10 kinases at 5μM (by <11% inhibition).