66-203-55MG

MilliporeSigma™ Calbiochem™ U-73122

Manufacturer: MilliporeSigma™

CAS Number: 112648-68-7

Select a Size

Pack Size SKU Availability Price
Each of 1 66-203-55MG-Each-of-1 In Stock ₹ 16,024.53

66-203-55MG - Each of 1

₹ 16,024.53

In Stock

Quantity

1

Base Price: ₹ 16,024.53

GST (18%): ₹ 2,884.415

Total Price: ₹ 18,908.945

Color

Off-white

Target Proteins

Agonist-induced phospholipase C activation

Molecular Formula

C29H40N2O3

Solubility

CHCl3, DMSO, or EtOH (Reconstitute in DMSO just prior to use)

Quantity

5 mg

Description

98% by HPLC

CAS

112648-68-7

Formula Weight

464.7g/mol

Form

Solid

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Description

  • Inhibits agonist-induced phospholipase C activation (IC 50 = 1-2.1μM) in human platelets and neutrophils
  • Inhibits ET-1 and parathyroid hormone-induced Ca 2+ transients (IC 50 = 800nM and 500 nM, respectively)
  • Also inhibits agonist-induced down-regulation of muscarinic receptors in SK-N-SH neuroblastoma cells
  • Acts as a potent inhibitor of human polymorphonuclear neutrophil adhesion on biological surfaces (IC 50 = 50 nM)
  • Reported to abolish T lymphoma cell invasion into fibroblast monolayers.