RAB0019
Human Amphiregulin ELISA Kit
for serum, plasma, cell culture supernatant and urine
Manufacturer: Sigma Aldrich
Synonym(S): AR
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 KIT | RAB0019-1-KIT | In Stock | ₹ 64,524.30 |
RAB0019 - 1 KIT
In Stock
Quantity
1
Base Price: ₹ 64,524.30
GST (18%): ₹ 11,614.374
Total Price: ₹ 76,138.674
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitablecapture ELISA: suitable
input
sample type plasmasample type cell culture supernatant(s)sample type urinesample type serum
assay range
inter-assay cv: <12%intra-assay cv: <10%sensitivity: 10 pg/mLstandard curve range: 16.46-4000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... AREG(374)
Related Products
Description
- General description: The Human Amphiregulin (AR) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human AR in serum, plasma, cell culture supernatants and urine.The AREG (amphiregulin) gene codes for a shedding ectodomain, derived from a transmembrane precursor of 252 amino acids. The encoded protein is released into blood or cellular vicinity through autocrine and paracrine.[1][2] Areg is predominantly expressed in epithelial, mesenchymal cells and also by active immune cells.[1] The AREG gene is mapped to human chromosome 4q13.3.[2]
- Immunogen: Recombinant Human Amphiregulin
- Application: Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)Human Amphiregulin ELISA Kit has been used to estimate the plasma concentration of amphiregulin by ELISA.[3]
- Biochem/physiol Actions: Areg (amphiregulin) stimulates growth-signaling pathways via EGF (epidermal growth factor) receptors. Areg participates in the organogenesis of mammary gland. It is regarded as a pro-oncogenic factor and contributes to tumor progression. Upregulation of the AREG gene is observed in cancer and resists chemotherapy.[1] AREG reduces E-cadherin expression in order to promote invasion and progression of ovarian cancer.[4]
- Other Notes: A sample Certificate of Analysis is available for this product.Please type the word sample in the text box provided for lot number.
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
WGK
WGK 3