C8946
α-Chymotrypsin from human pancreas
lyophilized powder
Manufacturer: Sigma Aldrich
CAS Number: 9004-07-3
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 VIAL | C8946-1-VIAL | In Stock | ₹ 71,506.20 |
C8946 - 1 VIAL
In Stock
Quantity
1
Base Price: ₹ 71,506.20
GST (18%): ₹ 12,871.116
Total Price: ₹ 84,377.316
biological source
human pancreas
Quality Level
200
form
lyophilized powder
mol wt
25 kDa
packaging
vial of ≥10 BTEE units
UniProt accession no.
P17538
storage temp.
−20°C
Gene Information
human ... CTRB1(1504)
Other Options
Related Products
Description
- General description: α-Chymotrypsin belongs to the trypsin family of serine proteases. It is secreted as an inactive precursor chymotrypsinogen to the intestine. The cleavage of peptide bond at amino acid 148 forms α-chymotrypsin.[1] Chymotrypsinogen is encoded by the gene CTRB1 and is mapped to 16q23.1 in the human chromosome.[2]
- Application: α-Chymotrypsin from human pancreas has been used to test inhibition by N-alkyl isatins against mammalian serine proteases.[3]
- Biochem/physiol Actions: A serine protease that hydrolyzes peptide bonds with aromatic or large hydrophobic side chains (Tyr, Trp, Phe, Met) on the carboxyl end of the bond.
- Unit Definition: One unit will hydrolyze 1.0 μmole of BTEE per min at pH 7.8 at 25°C.
- Analysis Note: Protein determined by A1%/280
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P261 - P264 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
WGK
WGK 1
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves