H2126
Hyaluronidase from sheep testes
Type II, lyophilized powder, ≥300 units/mg solid
Manufacturer: Sigma Aldrich
CAS Number: 37326-33-3
Synonym(S): Hyaluronate 4-glycanohydrolase, Hyaluronoglucosaminidase
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | H2126-100-MG | In Stock | ₹ 7,137.30 |
| 500 MG | H2126-500-MG | In Stock | ₹ 20,612.70 |
| 1 G | H2126-1-G | In Stock | ₹ 35,464.50 |
| 5 G | H2126-5-G | In Stock | ₹ 1,41,880.20 |
H2126 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 7,137.30
GST (18%): ₹ 1,284.714
Total Price: ₹ 8,422.014
conjugate
conjugate (Glucosaminoglycan)
Quality Level
200
type
Type II
form
lyophilized powder
specific activity
≥300 units/mg solid
mol wt
55 kDa
storage temp.
−20°C
Other Options
Related Products
Description
- General description: Hyaluronidase is a hyaluronic acid-metabolizing enzyme.[1] It is found in the venoms of snake, honeybee and hymenoptera. Hyaluronidase degrades hyaluronic acid (HA), which enhances membrane permeability, lowers viscosity and increases tissue permeability. It enhances the diffusion of local anesthetics, lowers the size of myocardial infarction, improves the effects of anticancer drugs and prevents perineal trauma during spontaneous delivery.[2]
- Application: Hyaluronidase from sheep testes has been used:in flow cytometry[3]in the isolation of putative spermatogonial stem cells (SSCs)[4]to study the effects of magnetic stimulation in magnetic hydrogel properties[5]in immunohistochemistry to visualize collagen type II distribution[6][7]to expose group-III auditory neurons of Muller′s organ for patch-clamp recordings[8]for the degeneration of hydrogels[9]
- Biochem/physiol Actions: These enzymes randomly cleave β-N-acetylhexosamine-(1−4)-glycosidic bonds in hyaluronic acid, chondroitin, and chondroitin sulfates.
- Unit Definition: One unit will degrade 0.75 μg of the polysaccharide hyaluronic acid per minute at pH 5.35 at 37 ºC (as measured by turbidimetric absorbance (λ: 600nm) when complexed with BSA after 45 minutes).
- Physical form: Lyophilized powder containing lactose
- Other Notes: View more information on enzymes for complex carbohydrate analysis at www.sigma-aldrich.com/enzymeexplorer
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Resp. Sens. 1
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves