SRP4647
Galectin-7 human
recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
Manufacturer: Sigma Aldrich
Synonym(S): Gal-7, Galactein 7, Galectin7, HKL-14, PI7, p53-induced gene 1 protein
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 μG | SRP4647-50-μG | In Stock | ₹ 40,711.40 |
SRP4647 - 50 μG
In Stock
Quantity
1
Base Price: ₹ 40,711.40
GST (18%): ₹ 7,328.052
Total Price: ₹ 48,039.452
biological source
human
recombinant
expressed in E. coli
Assay
≥98% (HPLC)≥98% (SDS-PAGE)
form
lyophilized
mol wt
~15.4 kDa
packaging
pkg of 50 μg
storage condition
avoid repeated freeze/thaw cycles
impurities
endotoxin, tested
NCBI accession no.
P47929
UniProt accession no.
P47929
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Description
- General description: LGALS7 (galectin-7) is from the galectin family of β-galactoside-binding proteins. It is mainly present in the stratified epithelia, hair follicles and thymic Hassall′s corpuscles. The protein localizes in the nucleus and cytoplasm, and exists as a homodimer.[1][2] Recombinant Human Galectin-7 is a 15.4kDa protein consisting of 136 amino acid residues
- Biochem/physiol Actions: LGALS7 (galectin-7) helps in maintaining skin homeostasis, particularly after skin injury. It is also involved in keratinocyte proliferation and differentiation via JNK1 (c-Jun N-terminal kinase)-miR-203-p63 pathway.[1] LGALS7 is a biomarker for skin condition and skin barrier disruption.[3] In HeLa cells, it induces apoptosis most likely via JNK signaling. LGALS7 is downregulated in SV40-transformed cells and squamous cell carcinoma cells.[1] Change in its activity/expression is associated with the progression of various epithelia-associated cancers.[4] LGALS7 also helps in postmenstrual endometrial re-epithelialization.[2]
- Physical form: Sterile filtered and Lyophilized without additives.
- Reconstitution: Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.