Description

• General description: Sodium formate is the colorless sodium salt of formic acid. It can be prepared by reacting formic acid with sodium hydroxide or carbonate.[1] Its crystal structure has been investigated. Its crystals exhibit monoclinic-holohedral symmetry.[2]
• Application: Engineering Redox Cofactor Balance for Improved 5-Methyltetrahydrofolate Production in Escherichia coli.: Sodium formate was used to manipulate redox cofactor balance, significantly enhancing the production of 5-methyltetrahydrofolate in E. coli, showcasing its potential in metabolic engineering applications (Yang et al., 2024).Intensity-dependent mass search for improving metabolite database matches in chemical isotope labeling LC-QTOF-MS-based metabolomics.: Sodium formate was utilized in isotope labeling for LC-QTOF-MS, improving metabolite database matching accuracy, thus enhancing metabolomics data quality (Li et al., 2023).High-Yield Synthesis of Enantiopure 1,2-Amino Alcohols from l-Phenylalanine via Linear and Divergent Enzymatic Cascades.: The study highlights sodium formate′s role in enzymatic cascades for the efficient synthesis of enantiopure amino alcohols, important intermediates in pharmaceutical synthesis (Corrado et al., 2022).UPLC-ESI-QTOF/MS and multivariate data analysis for blood plasma and serum metabolomics: effect of experimental artefacts and anticoagulant.: Sodium formate was used as a reference standard in UPLC-ESI-QTOF/MS, providing insights into minimizing experimental artefacts in blood plasma and serum metabolomics (Barri and Dragsted, 2013).