Description

• Application: Maximum a posteriori Bayesian methods out-perform non-compartmental analysis for busulfan precision dosing - This study underscores the importance of advanced pharmacokinetic modeling for Busulfan, an antineoplastic agent, enhancing dosing accuracy and therapeutic outcomes in clinical settings (Hughes et al., 2024). Beneficial effects of adipose-derived stromal vascular fraction on testicular injury caused by busulfan - Investigates the protective effects of stem cell derivatives against Busulfan-induced gonadal toxicity, contributing to fertility preservation research in oncology patients (Hekimoglu et al., 2024). Transcriptomic profile of human iPSC-derived podocyte-like cells exposed to a panel of xenobiotics - Discusses the cellular impact of Busulfan on kidney cell models, shedding light on its potential side effects and mechanisms of toxicity at a molecular level (Murphy et al., 2024). Time-efficient germ cell transplantation from goldfish (Carassius auratus) into adult common carp (Cyprinus carpio) - This unique study uses Busulfan for germ cell depletion before transplantation, showcasing its utility in veterinary and aquatic biology research (Vigoya et al., 2024).
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