α-Hederin
phyproof® Reference Substance
Manufacturer: Sigma Aldrich
CAS Number: 27013-91-8
Synonym(S): (3β,4α)-3-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy]-23-hydroxyolean-12-en-28-oic acid
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 20 MG | PHL89220-20-MG | In Stock | ₹ 56,376.60 |
PHL89220 - 20 MG
In Stock
Quantity
1
Base Price: ₹ 56,376.60
GST (18%): ₹ 10,147.788
Total Price: ₹ 66,524.388
grade
primary reference standard
product line
phyproof® Reference Substance
Assay
≥95.0% (HPLC)
form
solid
manufacturer/tradename
PhytoLab
storage temp.
2-8°C
SMILES string
C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)CO[C@H]2O[C@H]3CC[C@@]4(C)[C@@H](CC[C@]5(C)[C@@H]4CC=C6[C@@H]7CC(C)(C)CC[C@@]7(CC[C@@]56C)C(O)=O)[C@]3(C)CO)[C@H](O)[C@H](O)[C@H]1O
InChI
1S/C41H66O12/c1-21-28(44)30(46)31(47)33(51-21)53-32-29(45)24(43)19-50-34(32)52-27-11-12-37(4)25(38(27,5)20-42)10-13-40(7)26(37)9-8-22-23-18-36(2,3)14-16-41(23,35(48)49)17-15-39(22,40)6/h8,21,23-34,42-47H,9-20H2,1-7H3,(H,48,49)/t21-,23-,24-,25+,26+,27-,28-,29-,30+,31+,32+,33-,34-,37-,38-,39+,40+,41-/m0/s1
InChI key
KEOITPILCOILGM-LLJOFIFVSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Medchemexpress LLC HY-N0255 5mg Medchemexpress, alpha-Hederin CAS:27013-91-8 Purity:>98% | -- | ₹ 8,085.42 | |
| | Sigma Aldrich Fine Chemicals Biosciences alpha-Hederin primary reference standard | 27013-91-8 | 10MG | -- | ₹ 79,456.15 | |
| | α-Hederin | -- | ₹ 51,094.00 | |
| | α-Hederin | -- | ₹ 56,376.60 |
Related Products
Description
- General description: This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
- Application: α-Hederin as a potent inhibitor in cancer research: α-Hederin has been identified and validated as a potent inhibitor of the Wnt/β-catenin signaling pathway in breast cancer stem cells, offering a promising avenue for targeted cancer therapy and highlighting its role in anti-cancer pharmacological research (Saliu et al., 2024). α-Hederin in overcoming drug resistance: This natural triterpenoid saponin has shown efficacy in reprogramming miRNA activity to overcome paclitaxel resistance mediated by small extracellular vesicles in non-small cell lung cancer (NSCLC), reinforcing its potential as a valuable agent in respiratory research and cancer treatment (Chang et al., 2024). α-Hederin′s role in promoting ferroptosis in cancer: Research indicates that α-Hederin can induce ferroptosis and reverse chemoresistance to cisplatin in non-small cell lung cancer, providing insights into its mechanism as a cytotoxic agent and its applications in enhancing the efficacy of conventional chemotherapies (Han et al., 2024). Molecular mechanisms of α-Hederin in tumor progression: A review of the molecular mechanisms by which α-Hederin influences tumor progression highlights its potential uses in biochemistry and pharmaceutical research, particularly for its anti-inflammatory and anticancer properties (Meng et al., 2024).
- Other Notes: This compound is commonly found in plants of the genus: hedera
- Legal Information: phyproof is a registered trademark of PhytoLab GmbH & Co. KG
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable