Mouse IgG2b kappa Isotype Control (eBMG2b), Functional Grade, eBioscience™, Invitrogen™

Description

• Description: The monoclonal mouse IgG2b, kappa is useful as an isotype control immunoglobulin
• Applications Reported: This mouse IgG2b isotype control has been reported for use in flow cytometric analysis
• Applications Tested: This mouse IgG2b Isotype Control has been tested by flow cytometric analysis of normal human peripheral blood cells
• Use isotype control at the same concentration as experimental antibody
• Storage and handling: Use in a sterile environment
• Filtration: 0.2 μm post-manufacturing filtered
• Purity: Greater than 90%, as determined by SDS-PAGE
• Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay
• Aggregation: Less than 10%, as determined by HPLC
• Mouse IgG2b is a subtype of immunoglobulin G antibody that is produced by B cells in response to an antigen
• It is the third most abundant IgG subtype in the serum and plays a crucial role in the adaptive immune response
• Mouse IgG2b is composed of two heavy chains and two light chains, and it is involved in opsonization, complement activation, and antibody-dependent cell-mediated cytotoxicity
• It is also involved in the regulation of immune responses, including the activation of T cells and the inhibition of B cell activation
• Mouse IgG2b is widely used in research and diagnostic applications, including ELISA, Western blotting, and immunohistochemistry
• It is also used in therapeutic applications, such as immunotherapy and vaccine development.