DR4 Monoclonal Antibody (32A242), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-676-455-Each-of-1 | In Stock | ₹ 45,218.46 |
01-676-455 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,218.46
GST (18%): ₹ 8,139.323
Total Price: ₹ 53,357.783
Antigen
DR4
Classification
Monoclonal
Concentration
1.0 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
O00220
Gene Symbols
TNFRSF10A
Immunogen
Synthetic peptide corresponding to residues 2-21 of mature human DR4.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Western Blot
Clone
32A242
Conjugate
Unconjugated
Gene
TNFRSF10A
Gene Alias
APO2; CD261; cytotoxic TRAIL receptor; death receptor 4; DR4; MGC9365; sCD261; soluble CD261; soluble TRAIL; sTRAIL; TNF receptor superfamily member 10a; TNF-related apoptosis-inducing ligand receptor 1; TNFRSF10A; TRAIL R1; TRAIL receptor 1; TRAILR1; TRAIL-R1; TRAILR-1; tumor necrosis factor receptor superfamily member 10A; tumor necrosis factor receptor superfamily member 10a variant 2; tumor necrosis factor receptor superfamily, member 10a
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
8797
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Suggested positive control: Hela whole cell extract, HeLa cell lysate
- TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1
- The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family
- DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues
- Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms
- Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).