GLRA1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA528362-Each-of-1 | In Stock | ₹ 48,726.42 |
PIPA528362 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,726.42
GST (18%): ₹ 8,770.756
Total Price: ₹ 57,497.176
Antigen
GLRA1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GLRA1
Gene Alias
GLRA; Glra1; Glra2; glycine receptor; Glycine receptor 48 kDa subunit; glycine receptor alpha 1; glycine receptor strychnine-binding subunit; Glycine receptor subunit alpha-1; glycine receptor, alpha 1; glycine receptor, alpha 1 subunit; Glyr; GLYRA1; gra1; HKPX1; nmf11; oscillator; ot; spasmodic; spd; STHE
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
25674, 2741
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.43 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P07727, P23415
Gene Symbols
GLRA1
Immunogen
Recombinant fragment corresponding to a region within amino acids 35 and 256 of Human Glycine Receptor alpha1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Raji
- Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (95%), Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- GLRA1 is a subunit of a pentameric inhibitory glycine receptor, which mediates postsynaptic inhibition in the central nervous system
- Defects in GLRA1 are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome
- Multiple transcript variants encoding different isoforms have been found for GLRA1
- Glycine receptors (GlyR) that include GLRA1 are members of the cys-loop family of ligand-gated ion channels, responsible for mediating the inhibitory effects of glycine
- GLRA1 are widely distributed throughout the CNS, particularly within the hippocampus, spinal cord and brain stem
- Diseases associated with GLRA1 include Hyperekplexia, Hereditary 1 and Hyperekplexia.