50-161-14
GARP Monoclonal Antibody (YGIC86), PerCP-eFluor™ 710, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-161-14-Each-of-1 | In Stock | ₹ 39,272.04 |
50-161-14 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,272.04
GST (18%): ₹ 7,068.967
Total Price: ₹ 46,341.007
Antigen
GARP
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
G3XA59
Gene Symbols
LRRC32
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
434215
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
YGIC86
Conjugate
PerCP-eFluor 710
Gene
LRRC32
Gene Alias
AI426318; D11S833E; D11S833Eh; D7H11S833E; EG434215; Garp; garpin; Glycoprotein A repetitions predominant; leucine rich repeat containing 32; leucine-rich repeat-containing protein 32; Lrrc32; Transforming growth factor beta activator LRRC32
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: The YGIC86 monoclonal antibody reacts with mouse Glycoprotein A Repetitions Predomit (GARP, also known as Lrrc32 or Garpin)
- GARP is an approximately 80 kDa glycoprotein that is expressed on the cell surface
- Using northern blot, RT-PCR or microarray analyses, the expression of GARP has been reported in placenta, lung, kidney, heart, ovary, liver, skeletal muscle, and pancreas
- Protein expression has been observed on megakaryocytes, platelets and activated regulatory T (Treg) cells
- The expression of GARP on Treg cells has been reported to be necessary for the suppressive function of Treg cells, possibly related to its role as a cell surface receptor for LAP/TGF beta
- When looking for expression of GARP on platelets, it is recommended to use the Foxp3 Staining Buffer Set (cat
- 00-5523) to fix the platelets before staining with this YGIC86 monoclonal antibody
- Fixation/permeabilization is not necessary when staining Treg cells
- YGIC86 does not cross-react to rat GARP
- Applications Reported: This YGIC86 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This YGIC86 antibody has been tested by flow cytometric analysis of stimulated mouse splenocytes
- This can be used at less than or equal to 0.25 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- GARP, also known as leucine rich repeat containing 32, is a type I membrane protein with twenty-two leucine-rich repeats and a short intracytoplasmic region
- GARP was identified based on the analysis of gene expression profiling of Treg and Th cells following TCR stimulation
- Since GARP is expressed in CD4+, CD25+, FoxP3+ cells (Tregs), it may be a candidate for cell surface marker for Treg cells.