ER-HR3 Antibody (ER-HR3), Alexa Fluor™ 488, Novus Biologicals™

ER-HR3

Monoclonal

Alexa Fluor 488

50mM Sodium Borate with 0.05% Sodium Azide

Rat

Protein G purified

RUO

NB100-64931 recognizes the murine antigen ER-HR3. ER-HR3 is a cell surface antigen which is expressed by Langerhans cells in epithelium, a subset of mature macrophages and dendritic cells that are located predominantly in haematopoietic and lymphoid organs. Initial studies of ER-HR3 demonstrated expression on peripheral blood monocytes but recent studies suggest that expression is actually very low. During foetal development, ER-HR3 positive cells are localised to haemapoietic islands and are often associated with erythroid progenitor cells. The functions of the ER-HR3 antigen have not been established but reports suggest that the antigen may be involved in adult erythropoiesis and in the regulation of the immune response. Clone ER-HR3 does not inhibit T cell proliferation in antigen-specific T-cell proliferation studies. Clone ER-HR3 recognizes two proteins of approximately 69kD and 55kD under non-reducing conditions.

Store at 4C in the dark.

IgG2c

Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

ER-HR3

Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Hematopoiesis related macrophage

Adherent F1 (CBAxBL) bone marrow stormal cells.

0.125 mL

Primary

Mouse

Purified