eIF4E Monoclonal Antibody (5D11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA1089-Each-of-1 | In Stock | ₹ 48,811.98 |
PIMA1089 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,811.98
GST (18%): ₹ 8,786.156
Total Price: ₹ 57,598.136
Antigen
eIF4E
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide
Gene Accession No.
P06730, P63073
Gene Symbols
Eif4e
Immunogen
Full length human eIF4E produced in HEK293T cells
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Immunoprecipitation, Immunoprecipitation, Western Blot
Clone
5D11
Conjugate
Unconjugated
Gene
Eif4e
Gene Alias
AUTS19; CBP; EG668879; EIF4E; EIF-4E; EIF4E1; EIF4EL1; Eif4e-ps; EIF4F; eIF-4F 25 kDa subunit; eukaryotic translation initiation factor 4E; eukaryotic translation initiation factor 4E-like 1; eukaryotic translation initiation factor 4E-like protein; eukaryotic translation initiation factor 4-like protein; If4e; MGC111573; mRNA cap-binding protein; OTTHUMP00000219703; OTTHUMP00000219704; OTTHUMP00000219705; translation initiation factor eIF-4E
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
13684, 1977
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- MA1-089 detects eIF4E in human and mouse samples and has been successfully used in Western blot, immunofluorescence, immunocytochemistry and immunoprecipitation applications
- MA1-089 does not react with rat eIF4E
- The MA1-089 immunogen is full length human eIF4E produced in HEK293T cells
- eIF4E is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export
- All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide)
- EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs
- It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F
- The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis
- The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A, that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G.