PIMA1179

eIF5A Monoclonal Antibody (4E10G8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA1179-Each-of-1 In Stock ₹ 42,737.22

PIMA1179 - Each of 1

₹ 42,737.22

In Stock

Quantity

1

Base Price: ₹ 42,737.22

GST (18%): ₹ 7,692.70

Total Price: ₹ 50,429.92

Antigen

eIF5A

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P63241

Gene Symbols

EIF5A

Immunogen

Purified recombinant, full length human EIF5A (aa1-154) expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunocytochemistry, Western Blot

Clone

4E10G8

Conjugate

Unconjugated

Gene

EIF5A

Gene Alias

AA410058; D19Wsu54e; Eif4d; eIF-4D; Eif5a; eIF-5A; EIF5A1; eIF-5A1; eIF-5A-1; eIF5AI; eukaryotic initiation factor 5A; Eukaryotic initiation factor 5A isoform 1; eukaryotic translation initiation factor 5A; eukaryotic translation initiation factor 5A-1; MGC104255; MGC99547; OTTHUMP00000128384; Rev-binding factor; uORF A

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1984

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • MA1-179 detects EIF5A from human samples
  • MA1-179 has been successfully used in western blot, immunofluorescence, and flow cytometry applications
  • mRNA-binding protein involved in translation elongation
  • Has an important function at the level of mRNA turnover, probably acting downstream of decapping
  • Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity
  • With syntenin SDCBP, functions as a regulator of TP53/p53 and TP53/p53-dependent apoptosis
  • Regulates also TNF-alpha-mediated apoptosis
  • Mediates effects of polyamines on neuronal process extension and survival
  • May play an important role in brain development and function, and in skeletal muscle stem cell differentiation
  • Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.