Glypican 3 Monoclonal Antibody (GT2473), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA531552-Each-of-1 | In Stock | ₹ 45,646.26 |
PIMA531552 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
Glypican 3
Classification
Monoclonal
Concentration
0.4 mg/mL
Formulation
PBS with 20% glycerol and no preservative; pH 7
Gene Accession No.
P51654
Gene Symbols
GPC3
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human Glypican-3.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
GT2473
Conjugate
Unconjugated
Gene
GPC3
Gene Alias
defective in Simpson-Golabi-Behmel overgrowth syndrome; DGSX; glypican 3; glypican proteoglycan 3; glypican-3; Glypican-3 alpha subunit; Glypican-3 beta subunit; Gpc3; GTR22; GTR2-2; heparan sulphate proteoglycan; intestinal protein OCI-5; MXR7; OCI5; OCI-5; proteoglycan GPC3; SDYS; secreted glypican-3; SGB; SGBS; SGBS1
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
2719
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Keep as concentrated solution
- Predicted reactivity: Chimpanzee (96%), Bovine (81%)
- Positive Control: HepG2, HepG2 (24 μg/mL Tunicamycin treatment for 16 hr)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- GPC3 is a cell surface proteoglycan that bears heparan sulfate
- This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function
- Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage
- These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition
- Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS)
- SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.