89-933-486

Abnova™ Human ANPEP (967 amino acids) native Protein from human serum

Manufacturer: Abnova™

Select a Size

Pack Size SKU Availability Price
Each of 1 89-933-486-Each-of-1 In Stock ₹ 75,207.24

89-933-486 - Each of 1

₹ 75,207.24

In Stock

Quantity

1

Base Price: ₹ 75,207.24

GST (18%): ₹ 13,537.303

Total Price: ₹ 88,744.543

For Use With (Application)

Functional Study, SDS-PAGE

Gene ID (Entrez)

290

Name

ANPEP (Human) Native Protein

Purification Method

Saltprecipitation/Ion Exchange Chromatography/Gelfiltration

Quantity

10 ug

Regulatory Status

RUO

Common Name

ANPEP

Biological Activity

> 500mU/mg (L-Leu-pNA at 37°C, pH 7.2).

Protein Tag

None

Form

Liquid

Formulation

In 20mM Tris-HCl, 500mM NaCl, 1mM CaCl

Molecular Weight (g/mol)

110-130kDa

Preparation Method

Native protein purified from human serum

Quality Control Testing

15% SDS-PAGE Stained with Coomassie Blue

Storage Requirements

Store at -80°C. Aliquot to avoid repeated freezing and thawing.

Gene Alias

APN/CD13/LAP1/PEPN/gp150/p150

Gene Symbol

ANPEP

Species

Human

Expression System

Native protein purified from human serum

Purity or Quality Grade

>90% by SDS-PAGE

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Description

  • Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes
  • In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases
  • Its function in proximal tubular epithelial cells and other cell types is less clear
  • The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily
  • Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical
  • The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS
  • Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections
  • Defects in this gene appear to be a cause of various types of leukemia or lymphoma
  • [provided by RefSeq]