89-957-213
Abnova™ Human PLAU (high molecular weight) native Protein from human urine
Manufacturer: Abnova™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-957-213-Each-of-1 | In Stock | ₹ 91,977.00 |
89-957-213 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 91,977.00
GST (18%): ₹ 16,555.86
Total Price: ₹ 1,08,532.86
Concentration
3.27 mg/mL
Formulation
In 0.05M sodium acetate, 0.1M NaCl, pH 5.0 (1mM EDTA)
Molecular Weight (g/mol)
54kDa
Preparation Method
Native protein purified from human urine
Quantity
100 ug
Regulatory Status
RUO
Common Name
PLAU
Species
Human
Expression System
Native protein purified from human urine
Purity or Quality Grade
>95% by SDS-PAGE
For Use With (Application)
SDS-PAGE
Gene ID (Entrez)
5328
Name
PLAU (Human) Native Protein
Purification Method
Column chromatography using several resins
Storage Requirements
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Gene Alias
ATF/UPA/URK/UROKINASE/u-PA
Gene Symbol
PLAU
Protein Tag
None
Form
Liquid
Related Products
Description
- This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation
- A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding
- This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen
- Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain
- This two-chain derivative is also called HMW-uPA (high molecular weight uPA)
- HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment
- LMW-uPA is proteolytically active but does not bind to the uPA receptor
- Alternatively spliced transcript variants encoding different isoforms have been found for this gene
- [provided by RefSeq]