89-935-305

Abnova™ Human APOB native Protein from human plasma

Manufacturer: Abnova™

Select a Size

Pack Size SKU Availability Price
Each of 1 89-935-305-Each-of-1 In Stock ₹ 18,908.76

89-935-305 - Each of 1

₹ 18,908.76

In Stock

Quantity

1

Base Price: ₹ 18,908.76

GST (18%): ₹ 3,403.577

Total Price: ₹ 22,312.337

Accession Number

P04114

Formulation

Lyophilized from 10mM sodium deoxycholate, 50mM Na

Molecular Weight (g/mol)

550kDa

Preparation Method

Native protein purified from human plasma

Storage Requirements

Store at -80°C on dry atmosphere. Aliquot to avoid repeated freezing and thawing.

Gene Alias

FLDB

Gene Symbol

APOB

Protein Tag

None

Form

Lyophilized

For Use With (Application)

SDS-PAGE

Gene ID (Entrez)

338

Name

APOB (Human) Native Protein

Quantity

500 ug

Regulatory Status

RUO

Common Name

APOB

Species

Human

Expression System

Native protein purified from human plasma

Purity or Quality Grade

≥90% by SDS-PAGE

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Description

  • This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins
  • It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver
  • The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA
  • The two isoforms share a common N-terminal sequence
  • The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination
  • Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels
  • [provided by RefSeq]