89-943-790

Abnova™ Human F11 native Protein from human plasma

Manufacturer: Abnova™

Select a Size

Pack Size SKU Availability Price
Each of 1 89-943-790-Each-of-1 In Stock ₹ 82,479.84

89-943-790 - Each of 1

₹ 82,479.84

In Stock

Quantity

1

Base Price: ₹ 82,479.84

GST (18%): ₹ 14,846.371

Total Price: ₹ 97,326.211

Concentration

0.37 mg/mL

Formulation

In 4mM sodium acetate, 0.15 M NaCl, pH 5.3

Molecular Weight (g/mol)

80kDa

Preparation Method

Native protein purified from human plasma

Quantity

100 ug

Regulatory Status

RUO

Common Name

F11

Species

Human

Expression System

Native protein purified from human plasma

Purity or Quality Grade

>98% by SDS-PAGE

For Use With (Application)

SDS-PAGE

Gene ID (Entrez)

2160

Name

F11 (Human) Native Protein

Purification Method

Multi-step chromatography

Storage Requirements

Store at -80°C. Aliquot to avoid repeated freezing and thawing.

Gene Alias

FXI/MGC141891

Gene Symbol

F11

Protein Tag

None

Form

Liquid

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Description

  • This gene encodes coagulation factor XI of the blood coagulation cascade
  • This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds
  • During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds
  • This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX
  • Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality
  • [provided by RefSeq]