Invitrogen™ Human Factor V Native Protein

Description

• Factor V (human) Native Protein, RP-43126, from Invitrogen
• Coagulation factor V (or Proaccelerin) is an essential factor of the blood coagulation cascade
• This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation
• This generates a heavy chain and a light chain which are held together by calcium ions
• The active factor V is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin
• Defects in the Factor V gene can result various diseases including Factor V deficiency, thrombophilia due to activated protein C resistance, Budd-Chiari syndrome, Ischemic stroke, and recurrent pregnancy loss
• RP-43126 contains native human Factor V protein
• RP-43126 may be used as a positive control in many immunological assays
• The RP-43126 protein molecular weight is ∽330 kDa
• The product is of human blood/plasma origin
• Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests
• This product is to be used for IN VITRO research purposes only, and is not intended for clinical or diagnostic use!