H6166
Interferon α 2B human
IFN-α 2B, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture
Manufacturer: Sigma Aldrich
Synonym(S): IFN α 2B, IFN Alfa 2b, INF α 2B, INF Alfa 2b, Interferon Alfa 2b
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 μG | H6166-10-μG | In Stock | ₹ 33,100.20 |
| 5 X 10 μG | H6166-5-X-10-μG | In Stock | ₹ 1,44,078.00 |
H6166 - 10 μG
In Stock
Quantity
1
Base Price: ₹ 33,100.20
GST (18%): ₹ 5,958.036
Total Price: ₹ 39,058.236
biological source
human
Quality Level
100
recombinant
expressed in HEK 293 cells
Assay
≥95% (SDS-PAGE)
form
lyophilized powder
potency
≤0.12 ng/mL EC50
quality
endotoxin tested
mol wt
dimer 16 kDa (glycosylated)
packaging
poly bottle of 10 μg (in poly bottle)
manufacturer/tradename
HumanZyme
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Description
- General description: The interferon α 2 (IFN-α2) exists in three forms 2a, 2b and 2c. It consists of 165 amino acids and five α helices. IFN-α2B is found structurally stable at pH 7. The recombinant IFN-α is nonglycosylated compared to the natural human IFN-α.[1]
- Biochem/physiol Actions: Interferon α 2B (IFN-α 2B) belongs to the type I interferon protein family. It is produced by many cell types in response to viral infection. IFN-α 2B has antiproliferative and antitumor activities, as well as induction of apoptosis and the inflammatory response. It enhances the expression of MHC proteins by increasing the presentation of antigen peptides and activates cytotoxic T-cells.
- Physical form: Lyophilized from a 0.2 μm filtered solution of 1x PBS.
- Preparation Note: HumanKine IFN-α 2B is a glycosylated monomer expressed in HEK 293 cells with an apparent molecular mass of 16 kDa. Production in human 293 cells offers authentic glycosylation. Glycosylation contributes to stability in cell growth media and other applications.
- Analysis Note: The specific activity was determined by the dose-dependent proliferation of WISH (heteroploid human amnion cell line) in presence of VSV ( vesicular stomatitis virus).
- Legal Information: HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable