A1774

Amikacin disulfate salt

potency: 674-786 μg per mg (as amikacin base)

Manufacturer: Sigma Aldrich

CAS Number: 39831-55-5

Synonym(S): (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-(3-amino-3-deoxy-alpha-D-glucopyranosyloxy)-4-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-3-hydroxycyclohexyl]-2-hydroxybutanamide disulfate, Antibiotic BB-K8 sulfate

Select a Size

Pack Size SKU Availability Price
250 MG A1774-250-MG In Stock ₹ 6,570.78
1 G A1774-1-G In Stock ₹ 17,514.85
5 G A1774-5-G In Stock ₹ 57,556.53

A1774 - 250 MG

₹ 6,570.78

In Stock

Quantity

1

Base Price: ₹ 6,570.78

GST (18%): ₹ 1,182.74

Total Price: ₹ 7,753.52

biological source

synthetic

Quality Level

200

form

powder or crystals

potency

674-786 μg per mg (as amikacin base)

color

white to off-white

antibiotic activity spectrum

Gram-negative bacteriamycobacteria

Mode of action

protein synthesis | interferes

storage temp.

2-8°C

SMILES string

OS(O)(=O)=O.OS(O)(=O)=O.NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O

InChI

1S/C22H43N5O13.2H2O4S/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21;2*1-5(2,3)4/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36);2*(H2,1,2,3,4)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+;;/m0../s1

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Description

  • General description: Chemical structure: aminoglycoside
  • Application: Amikacin is an aminoglycoside antibiotic commonly used in the treatment of drug-resistant mycobacteria [1]. It is used to study organism-directed delivery of antibiotics as well as drug resistance [2].
  • Biochem/physiol Actions: Amikacin prevents bacterial protein synthesis by binding to the 30S ribosome subunit and inducing mRNA misreading.
  • Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place.

SAFETY INFORMATION

Pictograms

GHS08,GHS07

Signal Word

Warning

Hazard Statements

H317,H361fd

Precautionary Statements

P202 - P261 - P272 - P280 - P302 + P352 - P308 + P313

Hazard Classifications

Repr. 2 - Skin Sens. 1

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves