A2661

Acetylcholine chloride

suitable for cell culture

Manufacturer: Sigma Aldrich

CAS Number: 60-31-1

Synonym(S): ACh

Select a Size

Pack Size SKU Availability Price
25 G A2661-25-G In Stock ₹ 7,285.23
100 G A2661-100-G In Stock ₹ 20,026.25

A2661 - 25 G

₹ 7,285.23

In Stock

Quantity

1

Base Price: ₹ 7,285.23

GST (18%): ₹ 1,311.341

Total Price: ₹ 8,596.571

biological source

synthetic

Quality Level

200

Assay

~99%

form

powder

technique(s)

cell culture | mammalian: suitable

mp

146-150 °C (lit.)

solubility

water: 100 mg/mL, clear, colorless

shipped in

ambient

storage temp.

room temp

SMILES string

[Cl-].CC(=O)OCC[N+](C)(C)C

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Description

  • Application: Acetylcholine chloride has been used in the preparation of acetylcholine, that is used as a common vehicle for iontophoresis of acetylcholine (ACh).[1] It has also been used to treat aNS-1 derived neurons for cAMP (cyclic adenosine monophosphate) assay and also used to check their ability to influence G protein-coupled receptors (GPCRs).[2]
  • Biochem/physiol Actions: Acetylcholine chloride, injected at 20 mg/kg body weight, reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis . The cholinergic anti-inflammatory mechanism is probably mediated by interaction of acetylcholine with α7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6.

SAFETY INFORMATION

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves