B2434
Bleomycin sulfate from Streptomyces verticillus
Manufacturer: Sigma Aldrich
CAS Number: 9041-93-4
Synonym(S): Blenoxane, Bleo, Blexane
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 20 MG | B2434-20-MG | In Stock | ₹ 1,56,020.73 |
B2434 - 20 MG
In Stock
Quantity
1
Base Price: ₹ 1,56,020.73
GST (18%): ₹ 28,083.731
Total Price: ₹ 1,84,104.461
product line
BioXtra
Quality Level
200
form
crystalline
potency
1.5-2.0 units per mg
technique(s)
cell culture | mammalian: suitable
solubility
H2O: 20 mg/mL, clear, colorless
cation traces
Cu: ≤0.10%
antibiotic activity spectrum
Gram-negative bacteriaGram-positive bacterianeoplastics
Mode of action
DNA synthesis | interferes
storage temp.
2-8°C
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Lkt Laboratories CAS 9041-93-4, ≥90%, Mixture of glycopeptide bleomycin sulfate salts that induces DNA strand breaks and is used to treat various cancers. | -- | ₹ 25,818.59 | |
| | Selleck Chemical LLC Bleomycin Sulfate 10mg 9041-93-4 NSC125066 | -- | ₹ 20,431.73 | |
| | Cayman Chemical Bleomycin (sulfate) | 9041-93-4 | MFCD00070310 | 1 mg | -- | ₹ 3,730.42 | |
| | Cayman Chemical Bleomycin (sulfate), 9041-93-4, 50 mg | -- | ₹ 46,407.74 | |
| | Sigma Aldrich Fine Chemicals Biosciences Bleomycin sulfate United States Pharmacopeia (USP) Reference Standard | 9041-93-4 | 15MG | -- | ₹ 91,369.52 | |
| | Bleomycin sulfate | -- | ₹ 21,974.75 | |
| | Bleomycin sulfate | -- | ₹ 82,648.88 | |
| | Bleomycin sulfate from Streptomyces verticillus | -- | ₹ 1,06,539.65 | |
| | Bleomycin sulfate from Streptomyces verticillus | -- | ₹ 1,32,032.53 | |
| | Bleomycin sulfate from Streptomyces verticillus | -- | ₹ 21,671.65 - ₹ 99,871.45 |
Related Products
Description
- General description: Chemical structure: glycopeptide
- Application: Bleomycin Sulfate is an antineoplastic antibiotic isolated from Streptomyces verticillus. It is recommended for use as a cell culture agent at 10-100 μg/mL.
- Biochem/physiol Actions: Bleomycin sulfate binds to DNA, causes ssDNA scission at specific base sequences and inhibits DNA synthesis. This inhibitory action requires bleomycin to bind oxygen and a metal ion. It can also cleave RNA, to a lesser degree but more selectively. It acts as an inducer and regulator of apoptosis and inhibits tumor angiogenesis.
- Components: This product is a mixture of glycopeptides antibiotics containing Bleomycin A2 (70%) and B2(30%). Bleomycins differ from each other in the terminal amine and show varying biological activity.
- Caution: This product should be stored at 2-8°C.
- Preparation Note: The product is soluble in water in water at 20 mg/mL and is active for several days. A solution of 2 units/mL in 0.1 M neutral potassium phosphate should be used within 14 days. A solution is active for three months at 3 units/mL in normal saline.
- Other Notes: Keep container tightly closed in a dry and well-ventilated place, strongly hygroscopic
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Carc. 2 - Muta. 1B - Repr. 2
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves