B7510

Beauvericin

≥97% (HPLC), suitable for HPLC

Manufacturer: Sigma Aldrich

CAS Number: 26048-05-5

Synonym(S): cyclo(D-α-Hydroxyisovaleryl-L-N-methyl-Phe)3

Select a Size

Pack Size SKU Availability Price
5 MG B7510-5-MG In Stock ₹ 25,200.60

B7510 - 5 MG

₹ 25,200.60

In Stock

Quantity

1

Base Price: ₹ 25,200.60

GST (18%): ₹ 4,536.108

Total Price: ₹ 29,736.708

Quality Level

200

Assay

≥97% (HPLC)

form

powder or crystals

technique(s)

HPLC: suitable

color

white to off-white

storage temp.

2-8°C

SMILES string

CC(C)C1OC(=O)C(Cc2ccccc2)N(C)C(=O)C(OC(=O)C(Cc3ccccc3)N(C)C(=O)C(OC(=O)C(Cc4ccccc4)N(C)C1=O)C(C)C)C(C)C

InChI

1S/C45H57N3O9/c1-28(2)37-40(49)46(7)35(26-32-21-15-11-16-22-32)44(53)56-39(30(5)6)42(51)48(9)36(27-33-23-17-12-18-24-33)45(54)57-38(29(3)4)41(50)47(8)34(43(52)55-37)25-31-19-13-10-14-20-31/h10-24,28-30,34-39H,25-27H2,1-9H3

InChI key

GYSCAQFHASJXRS-UHFFFAOYSA-N

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Description

  • General description: Beauvericin is a cyclohexadepsipeptide from the fungus Beauveria bassiana that belongs to the enniatin antibiotic family.[1] It comprises three D-hydroxyisovaleryl and N-methylphenylalanyl residues each.[1]
  • Application: Beauvericin has been used as an antimicrobial bioactive compound to test its effect on engineered Saccharomyces cerevisiae strains.[2] It has also been used as a mycotoxin standard in the reverse-phase (RP) high-pressure liquid chromatography (HPLC) to quantify mycotoxins produced by Fusarium oxysporum isolates.[3]
  • Biochem/physiol Actions: Beauvericin (BEA) is a commercial entomopathogenic mycoinsecticide with antiviral, antibacterial, insecticidal, and cytotoxic properties.[1] It elicits apoptotic and nematicidal activities as well.[4] Beauvericin blocks multidrug efflux and Tor complex 1 (TORC1) kinase.[5] It possesses ionophoric functionality and favors channel formation in patches of ventricular myocytes and synthetic membranes.[6] It is shown to inhibit L-type voltage-dependent Ca2+ current in the neuroblastoma cells.[7]
  • Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves