C5793

Ceftriaxone disodium salt hemi(heptahydrate)

third-generation cephalosporin antibiotic

Manufacturer: Sigma Aldrich

CAS Number: 104376-79-6

Synonym(S): Ceftriaxone disodium hemiheptahydrate

Select a Size

Pack Size SKU Availability Price
250 MG C5793-250-MG In Stock ₹ 12,925.05
1 G C5793-1-G In Stock ₹ 36,058.08

C5793 - 250 MG

₹ 12,925.05

In Stock

Quantity

1

Base Price: ₹ 12,925.05

GST (18%): ₹ 2,326.509

Total Price: ₹ 15,251.559

Quality Level

200

form

powder or crystals

antibiotic activity spectrum

Gram-negative bacteriaGram-positive bacteria

Mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

SMILES string

O.O.O.O.O.O.O.[Na+].[Na+].CO\N=C(/C(=O)N[C@H]1C2SCC(CSC3=NC(=O)C(=O)N([Na])N3C)=C(N2C1=O)C([O-])=O)c4csc(N)n4.CO\N=C(/C(=O)N[C@H]5C6SCC(CSC7=NC(=O)C(=O)N([Na])N7C)=C(N6C5=O)C([O-])=O)c8csc(N)n8

InChI

1S/2C18H18N8O7S3.4Na.7H2O/c2*1-25-18(22-12(28)13(29)23-25)36-4-6-3-34-15-9(14(30)26(15)10(6)16(31)32)21-11(27)8(24-33-2)7-5-35-17(19)20-7;;;;;;;;;;;/h2*5,9,15H,3-4H2,1-2H3,(H5,19,20,21,23,27,29,31,32);;;;;7*1H2/q;;4*+1;;;;;;;/p-4/b2*24-8-;;;;;;;;;;;/t2*9-,15-;;;;;;;;;;;/m11.........../s1

InChI key

PMRZKYOXTPBIQF-MAODNAKNSA-J

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Description

  • General description: Chemical structure: ß-lactam
  • Application: Ceftriaxone was used to study drug-induced immune hemolytic anemias[1], prophylactic strategies to reduce neonatal encephalopathy[2], pentylenetetrazole-evoked convulsions[3], the effect of expression, binding, and inhibition of PDP1 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis.
  • Biochem/physiol Actions: Ceftriaxone is a third-generation cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls. It is effective against Gram-positive and Gram-negative bacteria. Ceftriaxone is thought to increase EAAT2 pump expression in the central nervous system and to reduce glutamatergic toxicity.[4]
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place.

SAFETY INFORMATION

Pictograms

GHS08,GHS07

Signal Word

Danger

Hazard Statements

H315,H317,H319,H334,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves