E1257
Epidermal Growth Factor from murine submaxillary gland
lyophilized powder, BioReagent, suitable for cell culture
Manufacturer: Sigma Aldrich
CAS Number: 62229-50-9
Synonym(S): EGF, Epidermal cell growth factor
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 0.1 MG | E1257-0.1-MG | In Stock | ₹ 39,662.80 |
E1257 - 0.1 MG
In Stock
Quantity
1
Base Price: ₹ 39,662.80
GST (18%): ₹ 7,139.304
Total Price: ₹ 46,802.104
biological source
mouse submaxillary glands
Quality Level
200
product line
BioReagent
Assay
≥98% (SDS-PAGE)
form
lyophilized powder
potency
0.02-2.0 ng/mL EC50
packaging
pkg of 0.1 mg
storage condition
avoid repeated freeze/thaw cycles
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
Other Options
Related Products
Description
- General description: Epidermal growth factor (EGF) is the member of EGF-like family of growth factors, that binds to EGF receptor.[1] It is majorly expressed in kidney,[2] parotid gland and salivary gland.[3]
- Application: Epidermal Growth Factor from murine submaxillary gland has been usedin studying its effects on the development of caustic esophageal stricture in rats[4]for preparation of MCF-10A cell line[5]for the culture of primary hair follicle stem cells from arbas cashmere goat (gHFSCs) and adhesion of hair follicles (HF)[6]
- Biochem/physiol Actions: Epidermal growth factor (EGF) blocks gastric acid and pepsin secretion and increases gastrointestinal cell proliferation.[7] EGF stimulates proliferation and migration in bone marrow stromal cells (BMSC), that gives rise to osteoblasts, chondrocytes and adipocytes.[8] It functions as a strong mitogenic factor for various cultured cells. Mutations in this gene is linked to hypomagnesemia.[1] EGF plays a major role in the maintenance of hair and skin development.[9]
- Physical form: Lyophilized from 0.2 μm filtered solution in ammonium acetate buffer.
- Preparation Note: Purified by gel filtration and ion-exchange chromatography.
- Analysis Note: The biological activity is measured in a proliferation assay using BALB/MK cells.
SAFETY INFORMATION
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves