F9507
Flumethasone
Manufacturer: Sigma Aldrich
CAS Number: 2135-17-3
Synonym(S): 6α,9α-Difluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 6α,9α-Difluoro-16α-methylprednisolone, 6α-Fluorodexamethasone
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 MG | F9507-50-MG | In Stock | ₹ 10,229.63 |
F9507 - 50 MG
In Stock
Quantity
1
Base Price: ₹ 10,229.63
GST (18%): ₹ 1,841.333
Total Price: ₹ 12,070.963
form
powder
Quality Level
200
color
white to off-white
solubility
acetic acid: 10 mg/mL
Mode of action
cell membrane | interferes
storage temp.
2-8°C
SMILES string
[H][C@@]12C[C@@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])C[C@H](F)C4=CC(=O)C=C[C@]34C
InChI
1S/C22H28F2O5/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-19(15,2)21(14,24)17(27)9-20(13,3)22(11,29)18(28)10-25/h4-5,7,11,13-14,16-17,25,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1
InChI key
WXURHACBFYSXBI-GQKYHHCASA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Flumethasone | -- | ₹ 10,229.63 | |
| | Pregna-1,4-diene-3,20-dione,6,9-difluoro-11,17,21-trihydroxy-16-methyl-, (6a,11b,16a)- | -- | ₹ 427.80 - ₹ 5,903.64 | |
| | 2135-17-3 | Pregna-1,4-diene-3,20-dione,6,9-difluoro-11,17,21-trihydroxy-16-methyl-, (6a,11b,16a)- | -- | ₹ 2,823.48 - ₹ 88,725.72 |
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Description
- Application: Flumethasone pivalate is a topical difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. A prompt decrease in inflammation, exudation and itching is experienced after application. It is commonly used in veterinary practice[1] and has been used in cortisol assays to study early porcine conceptus development[2].
- Biochem/physiol Actions: Flumethasone is a glucocorticoid receptor agonist used in studies on plasma transcortin binding. It binds to the nucleus causing a variety of genetic activation and repressions. The anti-inflammatory actions of flumethasone is thought to involve lipocortins and phospholipase A2 inhibitory proteins, which results in the inhibition of arachidonic acid and the control of prostaglandin and leukotriene biosynthesis. Flumethasone suppresses the immune system due to a decrease in the function of the lymphatic system, a reduction in immunoglobulin and complement concentrations, the precipitation of lymphocytopenia, and interference with antigen-antibody binding .
- Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.