Kanamycin disulfate salt from Streptomyces kanamyceticus
aminoglycoside antibiotic
Manufacturer: Sigma Aldrich
CAS Number: 64013-70-3
Synonym(S): Kanamycin Disulfate Salt, Kanamycin disulfate, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->4))-2-deoxy-D-Streptamine sulfate (1:2) (salt), Kanamycin A, Kanamycin acid sulfate
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 G | K1876-1-G | In Stock | ₹ 3,756.28 |
| 5 G | K1876-5-G | In Stock | ₹ 18,207.65 |
| 25 G | K1876-25-G | In Stock | ₹ 43,776.30 |
K1876 - 1 G
In Stock
Quantity
1
Base Price: ₹ 3,756.28
GST (18%): ₹ 676.13
Total Price: ₹ 4,432.41
biological source
Streptomyces kanamyceticus
Quality Level
200
form
powder
potency
~650 μg per mg
impurities
≤4% Kanamycin B
color
white to off-white
solubility
H2O: 10 mg/mL
antibiotic activity spectrum
Gram-negative bacteriaGram-positive bacteriamycobacteriamycoplasma
Mode of action
protein synthesis | interferes
SMILES string
OS(O)(=O)=O.OS(O)(=O)=O.NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | TOKU-E Kanamycin Acid Sulfate, for BioProcessing, 64013-70-3, 5 g | -- | ₹ 9,240.48 | |
| | Canamycin A disulfate salt hydrate | -- | ₹ 5,423.33 | |
| | Kanamycin disulfate salt from Streptomyces kanamyceticus | -- | ₹ 3,756.28 - ₹ 43,776.30 | |
| | 64013-70-3 | Kanamycin disulfate salt | -- | ₹ 2,053.44 - ₹ 14,202.96 |
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Description
- General description: Chemical structure: aminoglycoside
- Application: Kanamycin sulfate is a broad spectrum minoglycoside-antibiotic It is used as an additive in culture media for the isolation of group D Streptococci on Kanamycin Esculin Azide Agar (Mossel et al.) or for selection of transformed plant cells containing the neomycin phosphotransferase (for kanamycin resistance); on a kanamycin-medium[1][2]. Kanamycin has been used for electrophysiological recordings of outer hair cells and inner hair cells[3]. It is used to inhibit shoot regeneration from Siberian Elmleaf explants[4]. It is recommended for use in cell culture applications at 100 mg/mL.
- Biochem/physiol Actions: Mode of Action: The product acts by binding to the 70S ribosomal subunit, inhibiting translocation and eliciting miscoding. Mode of Resistance: Aminoglycoside-modifying enzymes (including acetyltransferase, phosphotransferase, nucleotidyltransferase) can alter this antibiotic, preventing its interaction with ribosomes.Antimicrobial Spectrum: Kanamycin sulfate is effective against gram-negative and gram-postiive bacteria, and mycoplasma.
- Caution: Solutions are stable at 37°C for approximately 5 days. Aqueous stock solutions can be stored at 2-8°C for long term storage.
- Preparation Note: Kanamycin acid sulfate is prepared by solubilizing kanamycin sulfate in dilute sulfuric acid and drying. The sulfate content is approximately 25%.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Repr. 1B
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves