L5037

Leptin from rat

≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder

Manufacturer: Sigma Aldrich

Synonym(S): OB

Select a Size

Pack Size SKU Availability Price
1 MG L5037-1-MG In Stock ₹ 29,151.73

L5037 - 1 MG

₹ 29,151.73

In Stock

Quantity

1

Base Price: ₹ 29,151.73

GST (18%): ₹ 5,247.311

Total Price: ₹ 34,399.041

recombinant

expressed in E. coli

Quality Level

200

sterility

non-sterile

Assay

≥97% (SDS-PAGE)

form

lyophilized powder

potency

≤0.8 ng/mL ED50

mol wt

16 kDa

impurities

≤1.0 EU/μg endotoxin

UniProt accession no.

P50596

shipped in

ambient

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Description

  • Application: Leptin from rat has been used:to check the effect of intranasal nerve growth factor (NGF) on NGF activity in the spinal cord of Sprague-Dawley rats[1]for validation of labelling for leptin-bearing cells of Sprague-Dawley rats[2]to study the effect of leptin on STAT3 (signal transducer and activator of transcription 3) phosphorylation in neural population of Sprague-Dawley rats[3]to study leptin response towards chemoreflex in nucleus of the solitary tract[4]in rats, to check the effect of association between leptin and neuronal nitric oxide pathway on penicillin-induced epileptiform activity[5]
  • Biochem/physiol Actions: In rodents with uncontrolled diabetes mellitus, leptin is crucial for normalizing hyperglycemia.[6] In the digestive tract, it also participates in the absorption of dietary molecules via controlling transporters activity.[7]
  • Physical form: Lyophilized from a 0.2 μm filtered solution with 4.5 mM NaHCO3.
  • Analysis Note: The biological activity is measured by its ability to induce proliferation of leptin-dependent human OB-R transfected murine BAF3 cells.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves