M8407

Methotrexate hydrate

powder, suitable for cell culture, BioReagent

Manufacturer: Sigma Aldrich

CAS Number: 133073-73-1

Synonym(S): 4-Amino-10-methylfolic acid hydrate, L-4-Amino-N10-methylpteroylglutamic acid hydrate, L-Amethopterin hydrate, Antifolan hydrate, MTX hydrate, Methylaminopterin hydrate

Select a Size

Pack Size SKU Availability Price
100 MG M8407-100-MG In Stock ₹ 26,606.70
500 MG M8407-500-MG In Stock ₹ 1,04,917.20

M8407 - 100 MG

₹ 26,606.70

In Stock

Quantity

1

Base Price: ₹ 26,606.70

GST (18%): ₹ 4,789.206

Total Price: ₹ 31,395.906

product line

BioReagent

Quality Level

200

Assay

≥98% (HPLC)

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

H2O: insoluble

antibiotic activity spectrum

neoplasticsparasites

Mode of action

enzyme | inhibits

storage temp.

−20°C

SMILES string

[H]O[H].CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O

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Description

  • Application: Methotrexate hydrate has been used: as a dihydrofolate (DHFR) inhibitor in sphere forming assay culture[1]as a component of dulbecco′ modified Eagle′s medium (DMEM) for selection of transfected cells[2][3] in viability and co-culture assays [4]
  • Biochem/physiol Actions: Methotrexate is a folic acid antagonist.[5]

SAFETY INFORMATION

Pictograms

GHS06,GHS08

Signal Word

Danger

Hazard Statements

H301,H315,H319,H360FD

Precautionary Statements

P202 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves