M8764
[Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone trifluoroacetate salt
≥95% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 75921-69-6
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | M8764-1-MG | In Stock | ₹ 27,030.03 |
M8764 - 1 MG
In Stock
Quantity
1
Base Price: ₹ 27,030.03
GST (18%): ₹ 4,865.405
Total Price: ₹ 31,895.435
biological source
synthetic (organic)
Quality Level
200
sterility
non-sterile
Assay
≥95% (HPLC)
form
powder
solubility
0.1% aqueous TFA: 1.00-1.04 mg/mL, clear, colorless
UniProt accession no.
P01189
shipped in
ambient
storage temp.
−20°C
SMILES string
OC(=O)C(F)(F)F.CCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc4c[nH]c5ccccc45)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N6CCC[C@H]6C(=O)N[C@@H](C(C)C)C(N)=O
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Echelon Biosciences Research Labs Alpha MSH [Nle4,D-Phe7] - 1 mg, CAS#: 75921-69-6 | -- | ₹ 9,445.82 | |
| | Medchemexpress LLC HY-N2466 1mg Medchemexpress, Melanotan I CAS:75921-69-6 Purity:>98% | -- | ₹ 4,491.90 | |
| | 75921-69-6 | a-Melanotropin (swine), 4-L-norleucine-7-D-phenylalanine- | -- | ₹ 7,529.28 - ₹ 17,368.68 |
Related Products
Description
- Amino Acid Sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
- General description: [Nle4, D-Phe7]-α-melanocyte stimulating hormone is a potent analogue of α;-melanocyte-stimulating hormone (α -MSH).[1] αMSH is a tridecapeptide, mostly produced by the cells in the brain, pituitary and in circulation.[2]
- Application: [Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone trifluoroacetate salt has been used to detect its effect on O2 consumption and CO2 production in C57BL/6 mice.1It is also used to determine its effect on leptin secretion in the primary cultures of differentiated adipocytes.[1][3]
- Biochem/physiol Actions: [Nle4, D-Phe7]-α-melanocyte stimulating hormone is 100 times more potent than α-MSH in stimulating melanoma tyrosinase, which is a rate limiting enzyme in melanin biosynthesis and is 26 times as potent as α-MSH in S91adenylate cyclase assay.[4] α –MSH has an essential role to play in melanin production in animals. It also regulates development of several skin diseases, including cutaneous inflammation and hyper-proliferative skin diseases.[5]
- Other Notes: Lyophilized from 0.1% TFA in H2O
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves