M9511

Minocycline hydrochloride

powder, antibiotic

Manufacturer: Sigma Aldrich

CAS Number: 13614-98-7

Synonym(S): Minomycin

Select a Size

Pack Size SKU Availability Price
25 MG M9511-25-MG In Stock ₹ 4,633.10
100 MG M9511-100-MG In Stock ₹ 12,091.53
250 MG M9511-250-MG In Stock ₹ 20,892.25
1 G M9511-1-G In Stock ₹ 62,135.50

M9511 - 25 MG

₹ 4,633.10

In Stock

Quantity

1

Base Price: ₹ 4,633.10

GST (18%): ₹ 833.958

Total Price: ₹ 5,467.058

form

powder

Quality Level

200

antibiotic activity spectrum

mycobacteria

Mode of action

protein synthesis | interferes

originator

Teva

storage temp.

2-8°C

SMILES string

Cl.CN(C)[C@H]1[C@@H]2C[C@@H]3Cc4c(ccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)N(C)C

InChI

1S/C23H27N3O7.ClH/c1-25(2)12-5-6-13(27)15-10(12)7-9-8-11-17(26(3)4)19(29)16(22(24)32)21(31)23(11,33)20(30)14(9)18(15)28;/h5-6,9,11,17,27,29-30,33H,7-8H2,1-4H3,(H2,24,32);1H/t9-,11-,17-,23-;/m0./s1

InChI key

GLMUAFMGXXHGLU-VQAITOIOSA-N

Related Products

Img

Sigma Aldrich

O4636

Assay (anhydrous basis) 95.0%-102.0...

Img

Sigma Aldrich

D8809

meets USP testing specifications...

Img

Sigma Aldrich

P8396

penicillin analog...

Img

Sigma Aldrich

D6140

powder or crystals, suitable for ce...

Img

Sigma Aldrich

L6004

≥90% (TLC)...

Img

Sigma Aldrich

N8028

≥90% (HPLC)...

Img

Sigma Aldrich

D9016

--

Description

  • General description: Chemical structure: tetracycline
  • Application: Minocycline hydrochloride has been used:to prepare nanoliposomes to check its effect on macrophages[2] for the inhibition of neuroinflammation[3] and neuropathic pain[4] to treat glioma in murine GL261 glioma cells[5]
  • Biochem/physiol Actions: Minocycline is a broad spectrum antibiotic with bacteriostatic function.[2][5] Minocycline has anti-inflammatory properties.[2][3] Minocycline inhibits lipopolysaccharide mediated inflammatory cytokine tumour necrosis factor (TNF-α) secretion by macrophages. Minocycline inhibits macrophage proliferation in a dose dependent manner.[2] Minocycline inhibits neuroinflammation in pre-plaque of Alzheimer′s disease-like amyloid pathology through inhibition of key inflammatory enzymes like inducible nitric oxide synthase (iNOS), matrix metalloproteinase 9 (MMP-9) and 5-lipoxygenase.[3] Minocycline inhibits endothelial cell proliferation and angiogenesis. Minocycline exhibits anti-tumor activity in glioma by inhibiting membrane type 1 matrix metalloproteinase (MT1-MMP).[5] Minocycline increases cognition and neuronal differentiation.[6] zMinocycline effectively reduces neuropathic pain by increasing the functions of nociceptin/orphanin FQ.[4]
  • Features and Benefits: This compound was developed by Teva. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
  • Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves