N3510

Niclosamide

Manufacturer: Sigma Aldrich

CAS Number: 50-65-7

Synonym(S): 2′,5-Dichloro-4′-nitrosalicylanilide

Select a Size

Pack Size SKU Availability Price
50 G N3510-50-G In Stock ₹ 14,234.88
250 G N3510-250-G In Stock ₹ 36,740.05

N3510 - 50 G

₹ 14,234.88

In Stock

Quantity

1

Base Price: ₹ 14,234.88

GST (18%): ₹ 2,562.278

Total Price: ₹ 16,797.158

form

powder

Quality Level

200

antibiotic activity spectrum

parasites

Mode of action

enzyme | inhibits

SMILES string

Oc1ccc(Cl)cc1C(=O)Nc2ccc(cc2Cl)[N+]([O-])=O

InChI

1S/C13H8Cl2N2O4/c14-7-1-4-12(18)9(5-7)13(19)16-11-3-2-8(17(20)21)6-10(11)15/h1-6,18H,(H,16,19)

InChI key

RJMUSRYZPJIFPJ-UHFFFAOYSA-N

Other Options

Image Product Name Manufacturer Price Range
Medchemexpress LLC HY-B0497 10g , Niclosamide CAS:50-65-7 Purity:>98%
-- ₹ 8,624.45
Medchemexpress LLC HY-B0497 500mg Medchemexpress, Niclosamide CAS:50-65-7 Purity:>98%
-- ₹ 4,491.90
MilliporeSigma™ Calbiochem™ Niclosamide
-- --
Selleck Chemical LLC Niclosamide 50mg 50-65-7 Niclocide
-- ₹ 15,092.78
Cayman Chemical Niclosamide, 50-65-7, 25 g
-- ₹ 4,894.03
Niclosamide (anhydrous)
-- ₹ 14,267.35
Niclosamide
-- ₹ 14,234.88 - ₹ 36,740.05
2',5-Dichloro-4'-nitrosalicylanilide
-- --
50-65-7 | 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
-- ₹ 1,540.08 - ₹ 23,186.76

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Description

  • Application: Niclosamide is a teniacide in the anthelmintic family. It is effective against cestodes that infect humans. Niclosamide is used to study the Wnt/Frizzled-1 signaling pathway. It is used to inhibit transcription and DNA binding of the NF-?B pathway and it increases ROS levels to induce apoptosis in acute myelogenous leukemia (AML) cells[1].
  • Biochem/physiol Actions: Niclosamide uncouples oxidative phosphorylation in the tapeworm and inhibits mitochondrial oxidative phosphorylation of parasitic helminths. It blocks tumor necrosis factor-induced IκBα phosphorylation, translocation of p65, and expression of NF-κΒ– regulated genes in AML cells.
  • Other Notes: 50g,250g

SAFETY INFORMATION

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves