O4000
Oxythiamine chloride hydrochloride
≥95% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 614-05-1
Synonym(S): 5-(2-Hydroxyethyl)-3-(4-hydroxy-2-methyl-5-pyrimidinylmethyl)-4-methylthiazolium chloride
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 G | O4000-1-G | In Stock | ₹ 4,633.10 |
| 5 G | O4000-5-G | In Stock | ₹ 11,106.45 |
O4000 - 1 G
In Stock
Quantity
1
Base Price: ₹ 4,633.10
GST (18%): ₹ 833.958
Total Price: ₹ 5,467.058
Quality Level
200
Assay
≥95% (HPLC)
form
powder
technique(s)
HPLC: suitable
color
white to off-white
storage temp.
−20°C
SMILES string
CC(N1)=NC=C(C[N+]2=CSC(CCO)=C2C)C1=O.Cl.[Cl-]
InChI
1S/C12H16N3O2S.2ClH/c1-8-11(3-4-16)18-7-15(8)6-10-5-13-9(2)14-12(10)17;;/h5,7,16H,3-4,6H2,1-2H3,(H,13,14,17);2*1H
InChI key
QHUYPZVMEJLSEB-UHFFFAOYSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Sigma Aldrich Fine Chemicals Biosciences Oxythiamine chloride hydrochloride >=95% (HPLC) | 614-05-1 | MFCD00050656 | 5G | -- | ₹ 16,769.76 | |
| | Oxythiamine chloride hydrochloride | -- | ₹ 4,633.10 - ₹ 11,106.45 | |
| | 614-05-1 | Oxythiamine, HCl | -- | ₹ 3,422.40 - ₹ 36,961.92 |
Related Products
Description
- General description: Oxythiamine is a thiamine antimetabolite and the source through diet is by consuming acidic thiamine rich foods.[1]
- Application: Oxythiamine chloride hydrochloride is suitable for use:as a reference standard for calibration curve generation in liquid chromatography-tandem mass spectrometry (LC-MS/MS) for oxythiamine pyrophosphate (OTPP) quantification in red blood cells[2] as a thiamine transport inhibitor in human mammary epithelial cells (HMEC) and breast cancer cell lines[3] in the synthesis of oxythiamineH picrolonate salt[4]
- Biochem/physiol Actions: Oxythiamine (OT) is a thiamine antagonist.[5] It is a transketolase inhibitor and is employed to study anti-metastatic mechanisms,[5] especially those involving metalloproteinases (MMP).[6] It significantly sensitizes human hepatocellular carcinoma cells (HCC) to sorafenib, favoring tumor suppression.[7]
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves