O4876

Oligomycin

from Streptomyces diastatochromogenes, ≥90% total oligomycins basis (HPLC), powder, antibiotic

Manufacturer: Sigma Aldrich

CAS Number: 1404-19-9

Select a Size

Pack Size SKU Availability Price
5 MG O4876-5-MG In Stock ₹ 10,045.60
25 MG O4876-25-MG In Stock ₹ 44,577.35
100 MG O4876-100-MG In Stock ₹ 1,05,392.20
250 MG O4876-250-MG In Stock ₹ 1,92,609.23

O4876 - 5 MG

₹ 10,045.60

In Stock

Quantity

1

Base Price: ₹ 10,045.60

GST (18%): ₹ 1,808.208

Total Price: ₹ 11,853.808

product name

Oligomycin from Streptomyces diastatochromogenes, ≥90% total oligomycins basis (HPLC)

Quality Level

200

Assay

≥90% total oligomycins basis (HPLC)

form

powder

antibiotic activity spectrum

fungi

Mode of action

enzyme | inhibits

storage temp.

−20°C

InChI

1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13+,17-15-,21-18+

InChI key

MNULEGDCPYONBU-ZUSSGZTJSA-N

Other Options

Image Product Name Manufacturer Price Range
MilliporeSigma™ Calbiochem™ Oligomycin
-- --
Sigma Aldrich Fine Chemicals Biosciences Oligomycin from Streptomyces diastatochromogenes >=90% total oligomycins basis (HPLC) | 1404-19-9 | MFCD01779388 | 250MG
-- ₹ 2,49,193.50
Oligomycin
-- ₹ 10,045.60 - ₹ 1,92,609.23
1404-19-9 | Oligomycin
-- ₹ 2,823.48 - ₹ 42,352.20

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Description

  • General description: Chemical structure: macrolide
  • Application: Oligomycin from Streptomyces diastatochromogenes is used:in the inhibition of mitochondrial ATP production Leigh syndrome (LS) cells.[1]in ATP-linked respiration and maximal capacity respiration assay in astrocytes.[2]in measurement of oxygen consumption rate (OCR) and extracellular acidification rates in breast cancer cell lines.[3]
  • Biochem/physiol Actions: Oligomycin belongs to the macrolide group of antibiotics.[4] It inhibits mitochondrial ATP-synthase enzyme and phosphoryl group transfer.[5] Oligomycin interacts with ATP synthase subunit-c in the Fo portion and impairs proton transport.[6]
  • Other Notes: A mixture of oligomycins A, B, and C.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves