P4875

D-Penicillamine

98-101%

Manufacturer: Sigma Aldrich

CAS Number: 52-67-5

Synonym(S): 3,3-Dimethyl-D-cysteine, 3-Mercapto-D-valine, D-(−)-2-Amino-3-mercapto-3-methylbutanoic acid

Select a Size

Pack Size SKU Availability Price
1 G P4875-1-G In Stock ₹ 4,990.33
5 G P4875-5-G In Stock ₹ 10,240.45
25 G P4875-25-G In Stock ₹ 22,353.63

P4875 - 1 G

₹ 4,990.33

In Stock

Quantity

1

Base Price: ₹ 4,990.33

GST (18%): ₹ 898.259

Total Price: ₹ 5,888.589

Quality Level

100

Assay

98-101%

form

powder

mp

210 °C (dec.) (lit.)

solubility

H2O: 100 mg/mL

Mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

SMILES string

CC(C)(S)[C@@H](N)C(O)=O

InChI

1S/C5H11NO2S/c1-5(2,9)3(6)4(7)8/h3,9H,6H2,1-2H3,(H,7,8)/t3-/m0/s1

InChI key

VVNCNSJFMMFHPL-VKHMYHEASA-N

Other Options

Image Product Name Manufacturer Price Range
Apexbio Technology LLC D-Penicillamine, 100mg CAS# 52-67-5
-- ₹ 4,534.68
Sigma Aldrich Fine Chemicals Biosciences D-Penicillamine | 52-67-5 | MFCD00064302 | 5g
-- ₹ 17,294.24
eMolecules​ Ambeed / (S)-2-Amino-3-mercapto-3-methylbutanoic acid / 50mg / 598441473 / A101389 / / 52-67-5 / [null] / 149.210 / C5H11NO2S
-- ₹ 1,978.15
Penicillamine
-- ₹ 24,496.98
Penicillamine
-- ₹ 14,072.50
Penicillamine
-- ₹ 40,756.13
D-Penicillamine
-- ₹ 4,990.33 - ₹ 22,353.63
D-Penicillamine
-- ₹ 171.12 - ₹ 8,556.00
Penicillamine
-- ₹ 4,278.00
52-67-5 | D-Penicillamine
-- ₹ 342.24 - ₹ 31,999.44

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Description

  • General description: D-Penicillamine is derived from the hydrolysis of the corresponding beta-lactam antibiotic.
  • Application: It is used as an antirheumatic and as a chelating agent in Wilson′s disease. It is used as a copper chelator to form mixed disulfides with cysteine or other sulfide media components. It is used to inactivate protein-1 DNA binding[1] and to inhibit the growth of asynchronous cultures of rabbit articular chondrocytes[2].
  • Biochem/physiol Actions: Penicillamine is a characteristic degradation product of penicillin type antibiotics. One atom of copper combines with two molecules of penicillamine. Penicillamine reduces excess cystine excretion in cystinuria. This is by disulfide interchange between penicillamine and cystine, which results in formation of a readily excreted penicillamine-cysteine disulfide. Penicillamine interferes with the formation of cross-links between tropocollagen molecules and cleaves them when newly formed. Penicillamine lowers IgM rheumatoid factor and depresses T-cell activity.
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place.

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Warning

Hazard Statements

H361d

Precautionary Statements

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 2

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves