SBR00041

Cefiderocol

Manufacturer: Sigma Aldrich

CAS Number: 1225208-94-5

Synonym(S): S-649266

Select a Size

Pack Size SKU Availability Price
2 MG SBR00041-2-MG In Stock ₹ 36,556.03

SBR00041 - 2 MG

₹ 36,556.03

In Stock

Quantity

1

Base Price: ₹ 36,556.03

GST (18%): ₹ 6,580.085

Total Price: ₹ 43,136.115

Assay

≥95% (HPLC)

Quality Level

100

form

solid

reaction suitability

reagent type: chelator

antibiotic activity spectrum

Gram-negative bacteria

Mode of action

protein synthesis | inhibits

storage temp.

−20°C

SMILES string

NC1=NC(/C(C(N[C@@H]2C(N3[C@@H]2SCC(C[N+]4(CCCC4)CCNC(C5=CC=C(O)C(O)=C5Cl)=O)=C3C([O-])=O)=O)=O)=N/OC(C(O)=O)(C)C)=CS1

InChI

1S/C30H34ClN7O10S2/c1-30(2,28(46)47)48-36-19(16-13-50-29(32)34-16)24(42)35-20-25(43)37-21(27(44)45)14(12-49-26(20)37)11-38(8-3-4-9-38)10-7-33-23(41)15-5-6-17(39)22(40)18(15)31/h5-6,13,20,26H,3-4,7-12H2,1-2H3,(H7-,32,33,34,35,36,39,40,41,42,44,45,46,47)/t20-,26-/m1/s1

InChI key

DBPPRLRVDVJOCL-FQRUVTKNSA-N

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Description

  • General description: Cefiderocol has been shown to be effective in preventing the emergence of resistant mutants but is not active against methicillin-resistant Staphylococcus aureus (MRSA) or colistin-resistant bacteria. This versatile compound finds applications in cell biology and biochemical research.
  • Application: Cefiderocol has been used:study bacterial infections and tracking their uptake in vivothe study of the activity of Cefiderocol against gram-negative bacteria[1]
  • Biochem/physiol Actions: Mode of Action: Cefiderocol binds to specific proteins called penicillin-binding proteins (PBPs) located on the bacterial cell wall. This binding affinity inhibits the synthesis of the bacterial cell wall, leading to cell lysis and bacterial death.Antimicrobial Spectrum: Cefiderocol has strong antimicrobial properties, especially against a wide spectrum of Gram-negative pathogens.[1][2] Due to its siderophore core it is also a natural iron-chelator, which adds to its antibacterial activities.[1]
  • Features and Benefits: High-quality antibiotic suitable for multiple research applicationsIdeal for Cell Biology and Biochemical research
  • Other Notes: For additional information on our range of Biochemicals, please complete this form.
  • Disclaimer: The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable