T4626

Nα-p-Tosyl-L-arginine methyl ester hydrochloride

≥98% (TLC), suitable for ligand binding assays

Manufacturer: Sigma Aldrich

CAS Number: 1784-03-8

Synonym(S): TAME hydrochloride

Select a Size

Pack Size SKU Availability Price
5 G T4626-5-G In Stock ₹ 7,534.20
25 G T4626-25-G In Stock ₹ 16,941.13
100 G T4626-100-G In Stock ₹ 48,712.50

T4626 - 5 G

₹ 7,534.20

In Stock

Quantity

1

Base Price: ₹ 7,534.20

GST (18%): ₹ 1,356.156

Total Price: ₹ 8,890.356

Assay

≥98% (TLC)

Quality Level

200

form

powder

technique(s)

ligand binding assay: suitable

color

white

mp

145-147 (lit.)

storage temp.

−20°C

SMILES string

Cl.COC(=O)[C@H](CCCNC(N)=N)NS(=O)(=O)c1ccc(C)cc1

InChI

1S/C14H22N4O4S.ClH/c1-10-5-7-11(8-6-10)23(20,21)18-12(13(19)22-2)4-3-9-17-14(15)16;/h5-8,12,18H,3-4,9H2,1-2H3,(H4,15,16,17);1H/t12-;/m0./s1

InChI key

JIQFFACVQXXHMY-YDALLXLXSA-N

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Description

  • Application: Nα-p-Tosyl-L-arginine methyl ester hydrochloride has been used as an esterolytic substrate to assess trypsin-like activity in midgut extracts.[1] It has also been used as a substrate for measuring trypsin activity of pancreatin[2] and human intestinal samples.[3]
  • Biochem/physiol Actions: Nα-p-Tosyl-L-arginine methyl ester (TAME) binds to anaphase-promoting complex (APC) and prevents its activation by Cdc20 and Cdh1.
  • Substrates: Substrate for trypsin,[4] thrombin,[4] plasmin,[5] and other proteases.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves