HATU
for peptide synthesis, Novabiochem®
Manufacturer: Sigma Aldrich
CAS Number: 148893-10-1
Synonym(S): HATU, 1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate, N-[(Dimethylamino)-1H-1,2,3-triazolo-[4,5-b]pyridin-1-ylmethylene]-N-methylmethanaminium hexafluorophosphate N-oxide
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 25 G | 8.51013-25-G | In Stock | ₹ 44,170.01 |
| 100 G | 8.51013-100-G | In Stock | ₹ 70,760.00 |
8.51013 - 25 G
In Stock
Quantity
1
Base Price: ₹ 44,170.01
GST (18%): ₹ 7,950.602
Total Price: ₹ 52,120.612
product name
HATU, Novabiochem®
Quality Level
300
product line
Novabiochem®
form
solid
reaction suitability
reaction type: Coupling Reactions
manufacturer/tradename
Novabiochem®
mp
186 °C (decomposes)
application(s)
peptide synthesis
storage temp.
2-8°C
InChI
1S/C10H15N6O/c1-14(2)10(15(3)4)17-16-9-8(12-13-16)6-5-7-11-9/h5-7H,1-4H3/q+1
Other Options
Related Products
Description
- General description: A highly efficient coupling reagent for solid and solution phase peptide synthesis. In comparative studies HATU has been found to give better coupling yields with less enantiomerization that HBTU, TBTU or PyBOP®[1,2,3]. It is particularly effective at coupling to N-alkyl amines where other coupling reagents give poor yields and is the preferred reagent for loading resins bearing secondary amino groups. Associated Protocols and Technical ArticlesGuide to Selection of Coupling ReagentsLiterature references[1] L. A. Carpino (1993) J. Am. Chem. Soc., 115, 4397. [2] F. Albericio, et al. (1998) J. Org. Chem., 63, 9678. [3] J. A. Carpino, et al., in "Innovation & Perspectives in Solid Phase Synthesis, 3rd International Symposium", R. Epton (Ed.), Mayflower Worldwide Ltd., 1994, pp. 95.
- Linkage: Replaces: 01-62-0041
- Analysis Note: Colour (visual): white to slight yellow to beigeAppearance of substance (visual): powderIdentity (IR): passes testIdentity (NMR, 1H): passes testSolubility (1 mmole in 2 ml DMF): clearly soluble
- Legal Information: Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P261 - P272 - P280 - P284 - P302 + P352 - P304 + P340 + P312
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
Storage Class Code
4.1A - Other explosive hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable