8.51090

TFFH

Tetramethylfluoroformamidinium hexafluorophosphate Novabiochem®

Manufacturer: Sigma Aldrich

CAS Number: 164298-23-1

Synonym(S): TFFH, Tetramethylfluoroformamidinium hexafluorophosphate,Fluoro-N,N,N′,N′-bis(tetramethylene)formamidinium hexafluorophosphate

Select a Size

Pack Size SKU Availability Price
5 G 8.51090-5-G In Stock ₹ 15,469.99
25 G 8.51090-25-G In Stock ₹ 54,787.97

8.51090 - 5 G

₹ 15,469.99

In Stock

Quantity

1

Base Price: ₹ 15,469.99

GST (18%): ₹ 2,784.598

Total Price: ₹ 18,254.588

Quality Level

200

product line

Novabiochem®

form

solid

reaction suitability

reaction type: Coupling Reactions

manufacturer/tradename

Novabiochem®

mp

104-109 °C

application(s)

peptide synthesis

storage temp.

2-8°C

InChI

1S/C5H12FN2/c1-7(2)5(6)8(3)4/h1-4H3/q+1

InChI key

JILUGXGJYPRQPA-UHFFFAOYSA-N

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Description

  • General description: TFFH is an in situ coupling reagents which smoothly converts protected amino acids to the corresponding acid fluoride in the presence of base [1]. Acid fluorides have proven are highly effective at coupling hindered amino acids such as α,α-disubstituted amino acids [2]. Associated Protocols and Technical ArticlesGuide to Selection of Coupling ReagentsLiterature references[1] L. A. Carpino, et al. (1995) J. Am. Chem. Soc., 117, 5401. [2] S. A. Triolo, et al. in ′Peptides 1996, Proc. of 24th European Peptide Symposium′, R. Ramage & R. Epton (Eds), Mayflower Scientific Ltd., Birmingham, 1998, pp. 839.
  • Analysis Note: Color (visual): white to slight yellow to beigeAppearance of substance (visual): powderAssay 1H-qNMR: ≥ 98.0 %Ratio Cation/anion in 19F-NMR integration: lot specific result1:5,7 to 1:6,3Identity (IR): passes test
  • Legal Information: Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFETY INFORMATION

Pictograms

GHS05,GHS07

Signal Word

Danger

Hazard Statements

H315 - H318 - H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable