Description

• General description: A mucolytic agent and thio-based antioxidant. Increases the cellular pool of free-radical scavengers. Inhibits HIV replication. Prevents apoptotic death of neuronal cells. Antidote for acetaminophen poisoning. May serve as a substrate for microsomal glutathione transferase. Induces apoptosis in human and rat smooth muscle cells.
• Application: Chlorpyrifos-induced suppression of the antioxidative defense system leads to cytotoxicity and genotoxicity in macrophages.: The study highlights the protective role of N-acetyl-L-cysteine against chlorpyrifos-induced oxidative damage in macrophages, emphasizing its importance in mitigating pesticide toxicity (Lu et al., 2024). N-Acetyl-L-Cysteine Attenuates Titanium Dioxide Nanoparticle (TiO2 NP)-Induced Autophagy in Male Germ Cells.: This research explores how N-acetyl-L-cysteine can mitigate the autophagic effects induced by titanium dioxide nanoparticles in male germ cells, suggesting its use in reproductive health (Shin et al., 2024).
• Packaging: Packaged under inert gas
• Warning: Toxicity: Standard Handling (A)
• Reconstitution: Following reconstitution aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 1 month at -20°C.
• Other Notes: Ortolani, O., et al. 2000. Am. J. Respir. Crit. Care Med. 161, 1907.Tsai, J.C., et al. 1996. J. Biol. Chem. 271, 3667.Ferrari, G., et al. 1995. J. Neurosci.15, 2857.Weinander, R., et al. 1994. J. Biol. Chem.269, 71.
• Legal Information: CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany