94646

Poly(ethylene glycol)

Manufacturer: Sigma Aldrich

CAS Number: 25322-68-3

Synonym(S): Polyethylene glycol, PEG

Select a Size

Pack Size SKU Availability Price
250 G 94646-250-G In Stock ₹ 3,669.68
1 KG 94646-1-KG In Stock ₹ 8,844.03

94646 - 250 G

₹ 3,669.68

In Stock

Quantity

1

Base Price: ₹ 3,669.68

GST (18%): ₹ 660.542

Total Price: ₹ 4,330.222

Quality Level

200

product line

BioUltra

form

powder or crystals (or flakes)

mol wt

Mr ~35000

impurities

insoluble matter:, passes filter test≤0.005% peroxides (as H2O2):

pH

5.5-7.0 (25 °C, 50 mg/mL in H2O)

mp

64-66 °C

solubility

H2O: 50 mg/mL at 25 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kgsulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kgAs: ≤0.1 mg/kgBa: ≤5 mg/kgBi: ≤5 mg/kgCa: ≤10 mg/kgCd: ≤5 mg/kgCo: ≤5 mg/kgCr: ≤5 mg/kgCu: ≤5 mg/kgFe: ≤5 mg/kgK: ≤200 mg/kgLi: ≤5 mg/kgMg: ≤5 mg/kgMn: ≤5 mg/kgMo: ≤5 mg/kgNa: ≤200 mg/kgNi: ≤5 mg/kgPb: ≤5 mg/kgSr: ≤5 mg/kgZn: ≤5 mg/kg

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Description

  • General description: Polyethylene glycol (PEG) is a polyether compound that is used as an additive in cosmetics, pharmaceuticals, and food.[1] It consists of repeated ethylene glycol units[-(CH2CH2O)n].[2]
  • Application: Poly(ethylene glycol) has been used: as a component of University of Wisconsin (UW) cold preservation solutions to stabilize the cell membrane of hepatocytes during temperature changes[3]as a component of the supercooling solution to study supercooling preservation technique of the rat liver for transplantation and to protect against hypothermic injury[4]to prepare aqueous phase for the fabrication of multicellular spheroid (MCS) cultures[4]
  • Biochem/physiol Actions: Polyethylene glycol (PEG) is a synthetic polymer that is used as a gold standard in bioconjugation and nanomedicine to extend blood circulation time and enhance drug efficacy.[5] It acts as an ice-modulator by preventing ice crystallization, which is beneficial for cellular membranes. PEG provides protection against hypothermic injury, like lipid peroxidation and cell membrane injury.[4] PEG-conjugated drugs are considered safe for use in humans and are approved by the U.S. Food and Drug Administration (FDA). PEG has several biomedical applications, including biosensing, imaging, and tissue engineering.[5] It also repels protein adsorption and lowers the liver uptake, which helps in coating nanoparticles.[6]

SAFETY INFORMATION

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves