A1287

5-Azacytidine

Hybri-Max™, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma

Manufacturer: Sigma Aldrich

CAS Number: 320-67-2

Synonym(S): 4-Amino-1-(β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one, Ladakamycin

Select a Size

Pack Size SKU Availability Price
1 VIAL A1287-1-VIAL In Stock ₹ 2,846.98

A1287 - 1 VIAL

₹ 2,846.98

In Stock

Quantity

1

Base Price: ₹ 2,846.98

GST (18%): ₹ 512.456

Total Price: ₹ 3,359.436

biological source

synthetic (organic)

Quality Level

200

grade

Hybri-Max™

sterility

γ-irradiated

product line

BioXtra

form

lyophilized powder

technique(s)

cell culture | hybridoma: suitable

impurities

endotoxin, tested

mp

226-232 °C (dec.) (lit.)

solubility

acetic acid: water (1:1): 5 mg/mL, clear, colorless

Related Products

Img

Sigma Aldrich

A9666

Hybri-Max™, γ-irradiated, lyophiliz...

Img

Sigma Aldrich

A4660

Hybri-Max™, 50 ×, γ-irradiated, lyo...

Img

Sigma Aldrich

A7422

γ-irradiated, lyophilized powder, B...

Img

Sigma Aldrich

A5159

Hybri-Max™, 50 ×, γ-irradiated, lyo...

Img

Sigma Aldrich

A1164

Hybri-Max™, γ-irradiated, 50x, lyop...

Img

Sigma Aldrich

A5539

γ-irradiated, lyophilized powder, B...

Img

Sigma Aldrich

A7824

≥99%, BioUltra...

Description

  • General description: Chemical structure: nucleoside
  • Application: 5-Azacytidine may be used to induce in vitro cardiomyogenic differentiation of adult human bone marrow mesenchymal stem cells.[1] It may also be used to study the effects of 5-Azacytidine on the immune regulatory myeloid-derived suppressor cells (MDSCs) and regulatory T cells (Tregs).[2]
  • Biochem/physiol Actions: 5-Azacytidine is a deoxycytidine analog and a demethylating agent.[3] It acts as a potential antineoplastic agent for acute myelogenous leukemia.[4] 5-Azacytidine activates repressed genes by inhibiting DNA methylation.[5] 5-Azacytidine also affects protein synthesis by altering the RNA function and stability.[4]
  • Reconstitution: Reconstitute contents of vial with 10 mL sterile cell culture medium. Stock solution is sufficient to prepare 500ml medium. Final working concentration: 10 μM 5-azacytidine.
  • Legal Information: Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

SAFETY INFORMATION

Pictograms

GHS08,GHS07,GHS09

Signal Word

Danger

Hazard Statements

H302,H341,H350,H360FD,H372,H410

Precautionary Statements

P202 - P260 - P264 - P273 - P301 + P312 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 1 - Carc. 1A - Muta. 2 - Repr. 1B - STOT RE 1

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves