Aminopterin
Hybri-Max™, 50 ×, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma
Manufacturer: Sigma Aldrich
CAS Number: 54-62-6
Synonym(S): (S)-2-{4-[(2,4-Diaminopteridin-6-yl)methylamino]benzamido}pentanedioic acid, 4-Amino-PGA, 4-Aminofolic acid, 4-Aminopteroyl-L-glutamic acid
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 VIALS | A5159-10-VIALS | In Stock | ₹ 9,412.80 |
A5159 - 10 VIALS
In Stock
Quantity
1
Base Price: ₹ 9,412.80
GST (18%): ₹ 1,694.304
Total Price: ₹ 11,107.104
biological source
synthetic
Quality Level
200
grade
Hybri-Max™
sterility
γ-irradiated
product line
BioXtra
form
lyophilized powder
concentration
50 ×
technique(s)
cell culture | hybridoma: suitable
impurities
endotoxin, tested
solubility
10 mL/vial, clear, red (in TC Medium)
Other Options
Related Products
Description
- Application: Aminopterin concentrate supplement for hybridoma cell culture applications.
- Biochem/physiol Actions: Folic acid antagonist. Aminopterin is actively transported into cells by the folate transporter. In the cell, it is converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase that, in turn, binds to dihydrofolate reductase and inhibits its activity. Aminopterin-polyglutamate is degraded intracellularly by γ-glutamyl hydrolase.
- Linkage: More potent, but more toxic, than methotrexate.
- Reconstitution: Reconstitute contents of vial with 10 mL sterile cell culture medium. Stock solution is sufficient to prepare 500 mL medium. Final working concentration: 0.4 μM aminopterin.
- Legal Information: Hybri-Max is a trademark of Sigma-Aldrich Co. LLC
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P202 - P264 - P270 - P301 + P310 - P302 + P352 - P305 + P351 + P338
Hazard Classifications
Acute Tox. 1 Oral - Eye Irrit. 2 - Muta. 2 - Repr. 1B - Skin Irrit. 2
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves