A2942

Amphotericin B

solution, suitable for cell culture, BioReagent

Manufacturer: Sigma Aldrich

CAS Number: 1397-89-3

Synonym(S): Amphotericin, Fungizone

Select a Size

Pack Size SKU Availability Price
20 ML A2942-20-ML In Stock ₹ 3,604.73
50 ML A2942-50-ML In Stock ₹ 7,112.03
100 ML A2942-100-ML In Stock ₹ 12,362.15

A2942 - 20 ML

₹ 3,604.73

In Stock

Quantity

1

Base Price: ₹ 3,604.73

GST (18%): ₹ 648.851

Total Price: ₹ 4,253.581

product name

Amphotericin B solution, 250 μg/mL in deionized water, 0.1 μm filtered, BioReagent, suitable for cell culture

Quality Level

200

sterility

0.1 μm filtered

product line

BioReagent

form

liquid

concentration

250 μg/mL in deionized water

technique(s)

cell culture | mammalian: suitable

color

yellow

antibiotic activity spectrum

fungiyeast

Mode of action

cell membrane | interferes

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Description

  • General description: Amphotericin B is a macrocyclic lactone with a hydrophilic polyhydroxyl chain and a lipophilic polyene based hydrocarbon chain.[1]
  • Application: Amphotericin B solution has been used:as an intraperitoneal injection for the treatment of Aspergillus fumigatus infection in mice[2] as a constituent of aspiration medium for the culture of Chinese Merino ewe ovaries as a constituent of transport medium during the collection of equine corpora lutea[3] as a supplement in RPMI medium for the culture of the mouse-mouse B cell hybridoma 55-6 cell line[4]
  • Biochem/physiol Actions: Amphotericin B is a polyene antifungal antibiotic from Streptomyces sp. that is clinically used to treat systemic fungal infections.[5] It has a high affinity for sterols, especially ergosterols, of both fungal and bacterial cell membranes. Normal usage in maintenance of antifungal cell cultures is 2.5 mg/L with penicillin and streptomycin used in the medium.
  • Packaging: 20,50,100ml
  • Components: This product is supplied as 250 μg/mL Amphotericin B in deionized water. It is a solution containing Amphotericin B, and the following components aimed to improve its solubility: sodium deoxycholate, sodium chloride and sodium phosphate.
  • Caution: Amphotericin B remains active for 3 days in culture at 37°C.
  • Preparation Note: It is not unusual for this material to form a precipitate in aqueous solutions. Mixing the solution will redissolve most of the precipitate but, if it does not fully resolubilize, the Amphotericin B will still be suitable for use.
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place. Light sensitive.

SAFETY INFORMATION

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves